human SHOX2 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human SHOX2.
shADV-222959
Ad-h-SHOX2-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human SHOX2 (short stature homeobox 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
OG12; OG12X; SHOT
Description (Vector)
SHOX2 is a member of the homeobox family of genes that encode proteins containing a 60-amino acid residue motif that represents a DNA binding domain. Homeobox genes have been characterized extensively as transcriptional regulators involved in pattern formation in both invertebrate and vertebrate species. Several human genetic disorders are caused by aberrations in human homeobox genes. This locus represents a pseudoautosomal homeobox gene that is thought to be responsible for idiopathic short stature, and it is implicated in the short stature phenotype of Turner syndrome patients. SHOX2 is considered to be a candidate gene for Cornelia de Lange syndrome. Alternative splicing results in multiple transcript variants.
Gene ID
6474
Gene Name (Vector)
short stature homeobox 2
Gene Symbol
SHOX2
HGNC ID
HGNC:10854
ORF Size (aa)
1068
RefSeq ID
NM_003030
RefSeq Synonyms
NM_006884, NM_003030, NM_001163678, BC008829,
Species
human
UniGene ID
Hs.55967
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.