human SGCG shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human SGCG.
shADV-222844
Ad-h-SGCG-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human SGCG (sarcoglycan gamma). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
35DAG; A4; DAGA4; DMDA; DMDA1; gamma-SG; LGMD2C; MAM; SCARMD2; SCG3
Description (Vector)
SGCG encodes gamma-sarcoglycan, one of several sarcolemmal transmembrane glycoproteins that interact with dystrophin. The dystrophin-glycoprotein complex (DGC) spans the sarcolemma and is comprised of dystrophin, syntrophin, alpha- and beta-dystroglycans and sarcoglycans. The DGC provides a structural link between the subsarcolemmal cytoskeleton and the extracellular matrix of muscle cells. Defects in the encoded protein can lead to early onset autosomal recessive muscular dystrophy, in particular limb-girdle muscular dystrophy, type 2C (LGMD2C).
Gene ID
6445
Gene Name (Vector)
sarcoglycan gamma
Gene Symbol
SGCG
HGNC ID
HGNC:10809
ORF Size (aa)
876
RefSeq ID
NM_000231
RefSeq Synonyms
NM_000231, BC109321, BC074778, BC074777,
Species
human
UniGene ID
Hs.37167
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.