human SFRS12 shRNA silencing Adenovirus

Name
Ad-h-SFRS12-shRNA

Cat No
shADV-222788

Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human SREK1.

shADV-222788

Ad-h-SFRS12-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human SREK1 (splicing regulatory glutamic acid and lysine rich protein 1). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

60

shRNA Validated

Yes

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

serine/arginine-rich-splicing regulatory protein 86; serine-arginine-rich splicing regulatory protein 508; SFRS12; splicing factor, arginine/serine-rich 12; splicing regulatory glutamic acid/lysine-rich protein 1; splicing regulatory glutamine/lysine-rich protein 1; Splicing regulatory protein 508; SRrp508; SRrp86

Description (eCommerce)

This gene SREK1 encodes Splicing regulatory glutamine/lysine-rich protein 1, a member of a family of serine/arginine-rich (SR) splicing proteins containing RNA recognition motif (RRM) domains. The encoded protein interacts with other SR proteins to modulate splice site selection [taken from NCBI Entrez Gene (Gene ID: 140890)].

Description (Vector)

SREK1 encodes a member of a family of serine/arginine-rich (SR) splicing proteins containing RNA recognition motif (RRM) domains. The encoded protein interacts with other SR proteins to modulate splice site selection. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene ID

140890

Gene Name (eCommerce)

splicing regulatory glutamic acid and lysine rich protein 1

Gene Name (Vector)

splicing regulatory glutamic acid and lysine rich protein 1

Gene Symbol

SREK1

HGNC ID

HGNC:17882

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

1527

ORF Size (bp)

1527 bp

Protein Name (eCommerce)

Splicing regulatory glutamine/lysine-rich protein 1

RefSeq ID

NM_139168

RefSeq Synonyms

NM_139168, NM_001323535, NM_001323534, NM_001323533, NM_001323529, NM_001323527, NM_001270492, NM_001077199, BC112343, BC067770,

Research Areas

Gene Expression,Mitochondrion,mRNA Processing,mRNA Splicing,RNA Processing

Research Areas (Faceted)

cell_biology,genetics,transcription_translation

Species

human

Target Sentence

This gene SREK1 encodes Splicing regulatory glutamine/lysine-rich protein 1, a member of a family of serine/arginine-rich (SR) splicing proteins containing RNA recognition motif (RRM) domains. The encoded protein interacts with other SR proteins to modulate splice site selection [taken from NCBI Entrez Gene (Gene ID: 140890)].

UniGene ID

Hs.519347

UniProt ID (eCommerce)

Q8WXA9

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.