human SFRP1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human SFRP1.
shADV-222780
Ad-h-SFRP1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human SFRP1 (secreted frizzled related protein 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
FRP; FRP-1; FRP1; FrzA; SARP2
Description (Vector)
SFRP1 encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. Members of this family act as soluble modulators of Wnt signaling; epigenetic silencing of SFRP genes leads to deregulated activation of the Wnt-pathway which is associated with cancer. SFRP1 may also be involved in determining the polarity of photoreceptor cells in the retina.
Gene ID
6422
Gene Name (Vector)
secreted frizzled related protein 1
Gene Symbol
SFRP1
HGNC ID
HGNC:10776
ORF Size (aa)
945
RefSeq ID
NM_003012
RefSeq Synonyms
NM_003012, BC036503,
Species
human
UniGene ID
Hs.713546
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.