human SETD3 shRNA silencing Adenovirus

Name 
Ad-h-SETD3-shRNA
Cat No 
shADV-222734
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human SETD3.

shADV-222734
Ad-h-SETD3-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human SETD3 (SET domain containing 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
C14orf154; histone-lysine N-methyltransferase setd3; SET domain-containing protein 3
Description (eCommerce)
Histone-lysine N-methyltransferase setd3 is a histone methyltransferase that methylates 'Lys-36' of histone H3 (H3K36me). H3 'Lys-36' methylation represents a specific tag for epigenetic transcriptional activation (by similarity) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q86TU7].
Gene ID
84193
Gene Name (eCommerce)
SET domain containing 3
Gene Name (Vector)
SET domain containing 3
Gene Symbol
SETD3
HGNC ID
HGNC:20493
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1785
ORF Size (bp)
1785 bp
Protein Name (eCommerce)
Histone-lysine N-methyltransferase setd3
RefSeq ID
NM_199123
RefSeq Synonyms
NM_199123, NM_032233, BC142995, BC066931, BC009054,
Research Areas
Histone Modification,Methyltransferase,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,transcription_translation
Species
human
Target Sentence
Histone-lysine N-methyltransferase setd3 is a histone methyltransferase that methylates 'Lys-36' of histone H3 (H3K36me). H3 'Lys-36' methylation represents a specific tag for epigenetic transcriptional activation (by similarity) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q86TU7].
UniGene ID
Hs.510407
UniProt ID (eCommerce)
Q86TU7

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.