human SERPINA3 shRNA silencing Adenovirus

Name 
Ad-h-SERPINA3-shRNA
Cat No 
shADV-222672
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human SERPINA3.

shADV-222672
Ad-h-SERPINA3-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human SERPINA3 (serpin family A member 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
AACT; ACT; GIG24; GIG25
Description (Vector)
SERPINA3 is a plasma protease inhibitor and member of the serine protease inhibitor class. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variations in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease.
Gene ID
12
Gene Name (Vector)
serpin family A member 3
Gene Symbol
SERPINA3
HGNC ID
HGNC:16
ORF Size (aa)
1272
ORF Size (bp)
1272 bp
RefSeq ID
NM_001085
RefSeq Synonyms
NM_001085, BC034554, BC010530, BC003559,
Species
human
UniGene ID
Hs.710488

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.