human SEPT9 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human SEPT9.
shADV-222620
Ad-h-SEPT9-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human SEPT9 (septin 9). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AF17q25; MLL septin-like fusion protein; MLL septin-like fusion protein MSF-A; MSF; MSF1; NAPB; Ov/Br septin; ovarian/breast septin; PNUTL4; SeptD1; septin D1; septin-9; SINT1
Description (eCommerce)
Septin 9 is a member of the septin family involved in cytokinesis and cell cycle control. This gene is a candidate for the ovarian tumor suppressor gene. Mutations in this gene cause hereditary neuralgic amyotrophy, also known as neuritis with brachial predilection. A chromosomal translocation involving this gene on chromosome 17 and the MLL gene on chromosome 11 results in acute myelomonocytic leukemia [taken from NCBI GeneID:10801].
Description (Vector)
9-Sep is a member of the septin family involved in cytokinesis and cell cycle control. 9-Sep is a candidate for the ovarian tumor suppressor gene. Mutations in this gene cause hereditary neuralgic amyotrophy, also known as neuritis with brachial predilection. A chromosomal translocation involving this gene on chromosome 17 and the MLL gene on chromosome 11 results in acute myelomonocytic leukemia. Multiple alternatively spliced transcript variants encoding different isoforms have been described.
Gene ID
10801
Gene Name (eCommerce)
septin 9
Gene Name (Vector)
septin 9
Gene Symbol
9-Sep
HGNC ID
HGNC:7323
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1269
ORF Size (bp)
1269 bp
Protein Name (eCommerce)
Septin-9
RefSeq ID
NM_006640
RefSeq Synonyms
NM_006640, NM_001293698, NM_001293697, NM_001293696, NM_001293695, NM_001113496, NM_001113495, NM_001113494, NM_001113493, NM_001113492, NM_001113491, BC054004, BC021192,
Research Areas
Cancer,Cell Cycle,Cell Division,Cytoskeleton,Tumor Suppressors/Oncoproteins
Research Areas (Faceted)
cancer,cell_biology,cell_cycle,genetics
Species
human
Target Sentence
Septin 9 is a member of the septin family involved in cytokinesis and cell cycle control. This gene is a candidate for the ovarian tumor suppressor gene. Mutations in this gene cause hereditary neuralgic amyotrophy, also known as neuritis with brachial predilection. A chromosomal translocation involving this gene on chromosome 17 and the MLL gene on chromosome 11 results in acute myelomonocytic leukemia [taken from NCBI GeneID:10801].
UniGene ID
Hs.440932
UniProt ID (eCommerce)
Q9UHD8
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.