human SEPT6 shRNA silencing Adenovirus

Name 
Ad-h-SEPT6-shRNA
Cat No 
shADV-222610
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human SEPT6.

shADV-222610
Ad-h-SEPT6-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human SEPT6 (septin 6). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
SEP2; SEPT2
Description (Vector)
6-Sep is a member of the septin family of GTPases. Members of this family are required for cytokinesis. One version of pediatric acute myeloid leukemia is the result of a reciprocal translocation between chromosomes 11 and X, with the breakpoint associated with the genes encoding the mixed-lineage leukemia and septin 2 proteins. 6-Sep encodes four transcript variants encoding three distinct isoforms. An additional transcript variant has been identified, but its biological validity has not been determined.
Gene ID
23157
Gene Name (Vector)
septin 6
Gene Symbol
6-Sep
HGNC ID
HGNC:15848
ORF Size (aa)
1305
ORF Size (bp)
1305 bp
RefSeq ID
NM_015129
RefSeq Synonyms
NM_145802, NM_145800, NM_145799, NM_015129, BC069231, BC036240, BC011922, BC009291,
Species
human
UniGene ID
Hs.496666

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.