human SEMA3A shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human SEMA3A.
shADV-222536
Ad-h-SEMA3A-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human SEMA3A (semaphorin 3A). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
coll-1; COLL1; HH16; Hsema-I; Hsema-III; SEMA1; SEMAD; SEMAIII; SEMAL; SemD
Description (Vector)
SEMA3A is a member of the semaphorin family and encodes a protein with an Ig-like C2-type (immunoglobulin-like) domain, a PSI domain and a Sema domain. This secreted protein can function as either a chemorepulsive agent, inhibiting axonal outgrowth, or as a chemoattractive agent, stimulating the growth of apical dendrites. In both cases, the protein is vital for normal neuronal pattern development. Increased expression of this protein is associated with schizophrenia and is seen in a variety of human tumor cell lines. Also, aberrant release of this protein is associated with the progression of Alzheimer's disease.
Gene ID
10371
Gene Name (Vector)
semaphorin 3A
Gene Symbol
SEMA3A
HGNC ID
HGNC:10723
ORF Size (aa)
2316
ORF Size (bp)
2316 bp
RefSeq ID
NM_006080
RefSeq Synonyms
NM_006080, BC111416,
Species
human
UniGene ID
Hs.252451
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.