human SEC61A1 shRNA silencing Adenovirus

Name 
Ad-h-SEC61A1-shRNA
Cat No 
shADV-222502
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human SEC61A1.

shADV-222502
Ad-h-SEC61A1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human SEC61A1 (Sec61 translocon alpha 1 subunit). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
HNFJ4; HSEC61; SEC61; SEC61A
Description (Vector)
SEC61A1 belongs to the SECY/SEC61- alpha family. It appears to play a crucial role in the insertion of secretory and membrane polypeptides into the endoplasmic reticulum. This protein found to be tightly associated with membrane-bound ribosomes, either directly or through adaptor proteins. This gene encodes an alpha subunit of the heteromeric SEC61 complex, which also contains beta and gamma subunits.
Gene ID
29927
Gene Name (Vector)
Sec61 translocon alpha 1 subunit
Gene Symbol
SEC61A1
HGNC ID
HGNC:18276
ORF Size (aa)
1428
ORF Size (bp)
1428 bp
RefSeq ID
NM_013336
RefSeq Synonyms
NM_013336, BC156688, BC152927, BC002951,
Species
human
UniGene ID
Hs.518236

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.