human SCNN1A shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human SCNN1A.
shADV-222377
Ad-h-SCNN1A-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human SCNN1A (sodium channel epithelial 1 alpha subunit). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
BESC2; ENaCa; ENaCalpha; SCNEA; SCNN1
Description (Vector)
Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the alpha subunit, and mutations in this gene have been associated with pseudohypoaldosteronism type 1 (PHA1), a rare salt wasting disease resulting from target organ unresponsiveness to mineralocorticoids. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Gene ID
6337
Gene Name (Vector)
sodium channel epithelial 1 alpha subunit
Gene Symbol
SCNN1A
HGNC ID
HGNC:10599
ORF Size (aa)
2010
ORF Size (bp)
2010 bp
RefSeq ID
NM_001038
RefSeq Synonyms
NM_001159576, NM_001159575, NM_001038, BC062613,
Species
human
UniGene ID
Hs.591047
Recently Viewed Products
Ad-h-POMT1-shRNA
Cat No: shADV-219437
Ad-h-SLC16A8-shRNA
Cat No: shADV-223138
AAV-m-2200002J24RIK-shRNA
Cat No: shAAV-250571
Ad-r-IL11RA1-shRNA
Cat No: shADV-290658
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.