human SALL3 shRNA silencing Adenovirus

Name 
Ad-h-SALL3-shRNA
Cat No 
shADV-222208
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human SALL3.

shADV-222208
Ad-h-SALL3-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human SALL3 (spalt like transcription factor 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
ZNF796
Description (Vector)
SALL3 encodes a sal-like C2H2-type zinc-finger protein, and belongs to a family of evolutionarily conserved genes found in species as diverse as Drosophila, C. elegans, and vertebrates. Mutations in some of these genes are associated with congenital disorders in human, suggesting their importance in embryonic development. This protein binds to DNA methyltransferase 3 alpha (DNMT3A), and reduces DNMT3A-mediated CpG island methylation. It is suggested that silencing of this gene, resulting in acceleration of DNA methylation, may have a role in oncogenesis.
Gene ID
27164
Gene Name (Vector)
spalt like transcription factor 3
Gene Symbol
SALL3
HGNC ID
HGNC:10527
ORF Size (aa)
2880
ORF Size (bp)
2880 bp
RefSeq ID
NM_171999
RefSeq Synonyms
NM_171999, BC148296,
Species
human
UniGene ID
Hs.700557

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.