human RPS3A shRNA silencing Adenovirus

Name 
Ad-h-RPS3A-shRNA
Cat No 
shADV-221907
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human RPS3A.

shADV-221907
Ad-h-RPS3A-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human RPS3A (ribosomal protein S3A). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
40S ribosomal protein S3a; FTE1; fte-1; MFTL; S3A; small ribosomal subunit protein eS1; v-fos transformation effector protein; v-fos transformation effector protein 1
Description (eCommerce)
Ribosomal Protein S3A/RPS3A may play a role during erythropoiesis through regulation of transcription factor DDIT3 [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P61247].
Description (Vector)
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S3AE family of ribosomal proteins. It is located in the cytoplasm. Disruption of the gene encoding rat ribosomal protein S3a, also named v-fos transformation effector protein, in v-fos-transformed rat cells results in reversion of the transformed phenotype. This gene is co-transcribed with the U73A and U73B small nucleolar RNA genes, which are located in its fourth and third introns, respectively. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Alternatively spliced transcript variants have been found for this gene.
Gene ID
6189
Gene Name (eCommerce)
ribosomal protein S3A
Gene Name (Vector)
ribosomal protein S3A
Gene Symbol
RPS3A
HGNC ID
HGNC:10421
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
795
Protein Name (eCommerce)
40S ribosomal protein S3a
RefSeq ID
NM_001006
RefSeq Synonyms
NM_001267699, NM_001006, BC071916, BC070211, BC066926, BC030161, BC019072, BC017123, BC009404, BC009219, BC006298, BC004981, BC001708, BC000204,
Research Areas
Apoptosis,Gene Expression,Host-Virus Interactions,Metabolism/Metabolic Process,mRNA Binding,RNA Binding,RNA Processing,Translational Control
Research Areas (Faceted)
cell_biology,genetics,transcription_translation,infectious_disease,metabolism,genetics,transcription_translation
Species
human
Target Sentence
Ribosomal Protein S3A/RPS3A may play a role during erythropoiesis through regulation of transcription factor DDIT3 [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P61247].
UniGene ID
Hs.356572
UniProt ID (eCommerce)
P61247

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.