human RPS14 shRNA silencing Adenovirus

Name
Ad-h-RPS14-shRNA

Cat No
shADV-221827

Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human RPS14.

shADV-221827

Ad-h-RPS14-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human RPS14 (ribosomal protein S14). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

shRNA Validated

Yes

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

40S ribosomal protein S14; emetine resistance; EMTB; S14; small ribosomal subunit protein uS11

Description (eCommerce)

Ribosomal protein S14 (RPS14) belongs to the S11P family of ribosomal proteins. It is located in the cytoplasm [taken from NCBI Entrez Gene (Gene ID: 6208)].

Description (Vector)

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S11P family of ribosomal proteins. It is located in the cytoplasm. Transcript variants utilizing alternative transcription initiation sites have been described in the literature. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. In Chinese hamster ovary cells, mutations in this gene can lead to resistance to emetine, a protein synthesis inhibitor. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.

Gene ID

6208

Gene Name (eCommerce)

ribosomal protein S14

Gene Name (Vector)

ribosomal protein S14

Gene Symbol

RPS14

HGNC ID

HGNC:10387

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

456

Protein Name (eCommerce)

40S ribosomal protein S14

RefSeq ID

NM_005617

RefSeq Synonyms

NM_005617, NM_001025071, NM_001025070, BC091474, BC020515, BC006784, BC003401, BC001126,

Research Areas

Gene Expression,Host-Virus Interactions,Metabolism/Metabolic Process,Mitochondrion,mRNA Binding,RNA Binding,RNA Processing,Translational Control

Research Areas (Faceted)

genetics,transcription_translation,infectious_disease,metabolism,cell_biology,genetics,transcription_translation

Species

human

Target Sentence

Ribosomal protein S14 (RPS14) belongs to the S11P family of ribosomal proteins. It is located in the cytoplasm [taken from NCBI Entrez Gene (Gene ID: 6208)].

UniGene ID

Hs.381126

UniProt ID (eCommerce)

P62263

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.