human RPLP1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human RPLP1.
shADV-221781
Ad-h-RPLP1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human RPLP1 (ribosomal protein lateral stalk subunit P1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
LP1; P1; RPP1
Description (Vector)
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal phosphoprotein that is a component of the 60S subunit. The protein, which is a functional equivalent of the E. coli L7/L12 ribosomal protein, belongs to the L12P family of ribosomal proteins. It plays an important role in the elongation step of protein synthesis. Unlike most ribosomal proteins, which are basic, the encoded protein is acidic. Its C-terminal end is nearly identical to the C-terminal ends of the ribosomal phosphoproteins P0 and P2. The P1 protein can interact with P0 and P2 to form a pentameric complex consisting of P1 and P2 dimers, and a P0 monomer. The protein is located in the cytoplasm. Two alternatively spliced transcript variants that encode different proteins have been observed. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
Gene ID
6176
Gene Name (Vector)
ribosomal protein lateral stalk subunit P1
Gene Symbol
RPLP1
HGNC ID
HGNC:10372
ORF Size (aa)
345
RefSeq ID
NM_001003
RefSeq Synonyms
NM_213725, NM_001003, BC007590, BC003369,
Species
human
UniGene ID
Hs.356502
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.