human RPL27A shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human RPL27A.
shADV-221649
Ad-h-RPL27A-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human RPL27A (ribosomal protein L27a). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
60S ribosomal protein L27a; L27A; large ribosomal subunit protein uL15
Description (eCommerce)
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. RPL27A is a ribosomal protein that is a component of the 60S subunit. RPL27A belongs to the L15P family of ribosomal proteins. It is located in the cytoplasm [taken from NCBI Entrez Gene (Gene ID: 6157)].
Description (Vector)
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L15P family of ribosomal proteins. It is located in the cytoplasm. Variable expression of this gene in colorectal cancers compared to adjacent normal tissues has been observed, although no correlation between the level of expression and the severity of the disease has been found. As is typical for genes encoding ribosomal proteins, multiple processed pseudogenes derived from this gene are dispersed through the genome.
Gene ID
6157
Gene Name (eCommerce)
ribosomal protein L27a
Gene Name (Vector)
ribosomal protein L27a
Gene Symbol
RPL27A
HGNC ID
HGNC:10329
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
447
Protein Name (eCommerce)
60S ribosomal protein L27a
RefSeq ID
NM_000990
RefSeq Synonyms
NM_000990, BC066326, BC014919, BC005326,
Research Areas
Gene Expression,Host-Virus Interactions,Metabolism/Metabolic Process,RNA Binding,RNA Processing,Translational Control
Research Areas (Faceted)
cell_biology,genetics,infectious_disease,metabolism,transcription_translation
Species
human
Target Sentence
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. RPL27A is a ribosomal protein that is a component of the 60S subunit. RPL27A belongs to the L15P family of ribosomal proteins. It is located in the cytoplasm [taken from NCBI Entrez Gene (Gene ID: 6157)].
UniGene ID
Hs.523463
UniProt ID (eCommerce)
P46776
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.