human RIN2 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human RIN2.
shADV-221244
Ad-h-RIN2-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human RIN2 (Ras and Rab interactor 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
MACS; RASSF4
Description (Vector)
The RAB5 protein is a small GTPase involved in membrane trafficking in the early endocytic pathway. The protein encoded by this gene binds the GTP-bound form of the RAB5 protein preferentially over the GDP-bound form, and functions as a guanine nucleotide exchange factor for RAB5. The encoded protein is found primarily as a tetramer in the cytoplasm and does not bind other members of the RAB family. Mutations in this gene cause macrocephaly alopecia cutis laxa and scoliosis (MACS) syndrome, an elastic tissue disorder, as well as the related connective tissue disorder, RIN2 syndrome. Alternative splicing results in multiple transcript variants.
Gene ID
54453
Gene Name (Vector)
Ras and Rab interactor 2
Gene Symbol
RIN2
HGNC ID
HGNC:18750
ORF Size (aa)
1389
ORF Size (bp)
1389 bp
RefSeq ID
NM_018993
RefSeq Synonyms
NM_018993, NM_001242581, BC128065,
Species
human
UniGene ID
Hs.472270
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.