human RHD shRNA silencing Adenovirus

Name 
Ad-h-RHD-shRNA
Cat No 
shADV-221164
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human RHD.

shADV-221164
Ad-h-RHD-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human RHD (Rh blood group D antigen). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CD240D; DIIIc; RH; RH30; Rh4; RHCED; RhDCw; RHDel; RHDVA(TT); RhII; RhK562-II; RhPI; RHPII; RHXIII
Description (Vector)
The Rh blood group system is the second most clinically significant of the blood groups, second only to ABO. It is also the most polymorphic of the blood groups, with variations due to deletions, gene conversions, and missense mutations. The Rh blood group includes this gene, which encodes the RhD protein, and a second gene that encodes both the RhC and RhE antigens on a single polypeptide. The two genes, and a third unrelated gene, are found in a cluster on chromosome 1. The classification of Rh-positive and Rh-negative individuals is determined by the presence or absence of the highly immunogenic RhD protein on the surface of erythrocytes. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID
6007
Gene Name (Vector)
Rh blood group D antigen
Gene Symbol
RHD
HGNC ID
HGNC:10009
ORF Size (aa)
966
RefSeq ID
NM_016124
RefSeq Synonyms
NM_016124, NM_001282872, NM_001282871, NM_001282870, NM_001282869, NM_001282868, NM_001282867, NM_001127691, BC160075, BC139922,
Species
human
UniGene ID
Hs.647623

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.