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human RCHY1 shRNA silencing Adenovirus

Name 
Ad-h-RCHY1-shRNA
Cat No 
shADV-220944
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human RCHY1.

shADV-220944
Ad-h-RCHY1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human RCHY1 (ring finger and CHY zinc finger domain containing 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
ARNIP; CHIMP; PIRH2; PRO1996; RNF199; ZCHY; ZNF363
Description (Vector)
RCHY1 has ubiquitin ligase activity. It mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including TP53, HDAC1 and CDKN1B, thus regulating their levels and cell cycle progression. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Gene ID
25898
Gene Name (Vector)
ring finger and CHY zinc finger domain containing 1
Gene Symbol
RCHY1
HGNC ID
HGNC:17479
ORF Size (aa)
786
RefSeq ID
NM_015436
RefSeq Synonyms
NM_015436, NM_001278539, NM_001278538, NM_001278537, NM_001278536, NM_001009922, NM_001008925, BC047393, BC031057,
Species
human
UniGene ID
Hs.48297

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.