human RBAK shRNA silencing Adenovirus

Name 
Ad-h-RBAK-shRNA
Cat No 
shADV-220822
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human RBAK.

shADV-220822
Ad-h-RBAK-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human RBAK (RB associated KRAB zinc finger). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
ZNF769
Description (Vector)
RBAK encodes a nuclear protein which interacts with the tumor suppressor retinoblastoma 1. The two interacting proteins are thought to act as a transcriptional repressor for promoters which are activated by the E2F1 transcription factor. This protein contains a Kruppel-associated box (KRAB), which is a transcriptional repressor motif. Read-through transcripts that include exons from the downstream gene LOC389458 are expressed from this locus.
Gene ID
57786
Gene Name (Vector)
RB associated KRAB zinc finger
Gene Symbol
RBAK
HGNC ID
HGNC:17680
ORF Size (aa)
2145
ORF Size (bp)
2145 bp
RefSeq ID
NM_021163
RefSeq Synonyms
NM_021163, NM_001204456, BC136676, BC136675,
Species
human
UniGene ID
Hs.396178

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.