human RASGRP3 shRNA silencing Adenovirus

Name 
Ad-h-RASGRP3-shRNA
Cat No 
shADV-220781
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human RASGRP3.

shADV-220781
Ad-h-RASGRP3-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human RASGRP3 (RAS guanyl releasing protein 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
GRP3
Description (Vector)
Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RASGRP3, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 (PubMed 10934204)).(supplied by OMIM, Mar 2008)
Gene ID
25780
Gene Name (Vector)
RAS guanyl releasing protein 3
Gene Symbol
RASGRP3
HGNC ID
HGNC:14545
ORF Size (aa)
2073
ORF Size (bp)
2073 bp
RefSeq ID
NM_170672
RefSeq Synonyms
NM_170672, NM_015376, NM_001139488, BC027849,
Species
human
UniGene ID
Hs.143674

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.