human RASD1 shRNA silencing Adenovirus

Name 
Ad-h-RASD1-shRNA
Cat No 
shADV-220769
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human RASD1.

shADV-220769
Ad-h-RASD1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human RASD1 (ras related dexamethasone induced 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
AGS1; DEXRAS1; MGC:26290
Description (Vector)
RASD1 encodes a member of the Ras superfamily of small GTPases and is induced by dexamethasone. The encoded protein is an activator of G-protein signaling and acts as a direct nucleotide exchange factor for Gi-Go proteins. This protein interacts with the neuronal nitric oxide adaptor protein CAPON, and a nuclear adaptor protein FE65, which interacts with the Alzheimer's disease amyloid precursor protein. RASD1 may play a role in dexamethasone-induced alterations in cell morphology, growth and cell-extracellular matrix interactions. Epigenetic inactivation of this gene is closely correlated with resistance to dexamethasone in multiple myeloma cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene ID
51655
Gene Name (Vector)
ras related dexamethasone induced 1
Gene Symbol
RASD1
HGNC ID
HGNC:15828
ORF Size (aa)
846
RefSeq ID
NM_016084
RefSeq Synonyms
NM_016084, NM_001199989, BC018041,
Species
human
UniGene ID
Hs.25829

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.