human RASAL2 shRNA silencing Adenovirus

Name 
Ad-h-RASAL2-shRNA
Cat No 
shADV-220768
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human RASAL2.

shADV-220768
Ad-h-RASAL2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human RASAL2 (RAS protein activator like 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
65
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
NGAP; ras GTPase-activating protein nGAP; Ras protein activator like 1; RAS protein activator-like 2; RASAL2/ACVR1 fusion
Description (eCommerce)
RAS protein activator like 2 (RASAL2) contains a GAP-related domain which is a characteristic domain of GTPase-activating proteins (GAPs). RASAL2 is highly homologous to Ras-specific GTPase activating proteins (RasGAPs).
Description (Vector)
RASAL2 encodes a protein that contains the GAP-related domain (GRD), a characteristic domain of GTPase-activating proteins (GAPs). GAPs function as activators of Ras superfamily of small GTPases. The protein encoded by this gene is able to complement the defective RasGAP function in a yeast system. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Gene ID
9462
Gene Name (eCommerce)
RAS protein activator like 2
Gene Name (Vector)
RAS protein activator like 2
Gene Symbol
RASAL2
HGNC ID
HGNC:9874
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3789
ORF Size (bp)
3789 bp
Protein Name (eCommerce)
Ras GTPase-activating protein nGAP
RefSeq ID
NM_004841
RefSeq Synonyms
NM_170692, NM_004841, BC110611,
Research Areas
Signal Transduction,TNF Signaling
Research Areas (Faceted)
signal_transduction,signal_transduction
Species
human
Target Sentence
RAS protein activator like 2 (RASAL2) contains a GAP-related domain which is a characteristic domain of GTPase-activating proteins (GAPs). RASAL2 is highly homologous to Ras-specific GTPase activating proteins (RasGAPs).
UniGene ID
Hs.715627
UniProt ID (eCommerce)
Q9UJF2

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.