human RASA3 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human RASA3.
shADV-220760
Ad-h-RASA3-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human RASA3 (RAS p21 protein activator 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
GAP1IP4BP; GAPIII
Description (Vector)
RASA3 is member of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This family member is an inositol 1,3,4,5-tetrakisphosphate-binding protein, like the closely related RAS p21 protein activator 2. The two family members have distinct pleckstrin-homology domains, with this particular member having a domain consistent with its localization to the plasma membrane.
Gene ID
22821
Gene Name (Vector)
RAS p21 protein activator 3
Gene Symbol
RASA3
HGNC ID
HGNC:20331
ORF Size (aa)
2505
ORF Size (bp)
2505 bp
RefSeq ID
NM_007368
RefSeq Synonyms
NM_007368, NM_001320822, NM_001320821, BC047242, BC038456,
Species
human
UniGene ID
Hs.593075
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.