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human RAP1B shRNA silencing Adenovirus

Name 
Ad-h-RAP1B-shRNA
Cat No 
shADV-220715
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human RAP1B.

shADV-220715
Ad-h-RAP1B-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human RAP1B (RAP1B, member of RAS oncogene family). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
K-REV; RAL1B
Description (Vector)
RAP1B encodes a member of the RAS-like small GTP-binding protein superfamily. Members of this family regulate multiple cellular processes including cell adhesion and growth and differentiation. This protein localizes to cellular membranes and has been shown to regulate integrin-mediated cell signaling. This protein also plays a role in regulating outside-in signaling in platelets. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 3, 5, 6 and 9.
Gene ID
5908
Gene Name (Vector)
RAP1B, member of RAS oncogene family
Gene Symbol
RAP1B
HGNC ID
HGNC:9857
ORF Size (aa)
555
RefSeq ID
NM_015646
RefSeq Synonyms
NM_015646, NM_001251922, NM_001251921, NM_001251918, NM_001251917, NM_001010942, BC095467, BC078173, BC000176,
Species
human
UniGene ID
Hs.369920

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.