human RAP1A shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human RAP1A.
shADV-220714
Ad-h-RAP1A-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human RAP1A (RAP1A, member of RAS oncogene family). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
C21KG; G-22K; KREV-1; KREV1; RAP1; SMGP21
Description (Vector)
The product of this gene belongs to the family of RAS-related proteins. These proteins share approximately 50% amino acid identity with the classical RAS proteins and have numerous structural features in common. The most striking difference between RAP proteins and RAS proteins resides in their 61st amino acid: glutamine in RAS is replaced by threonine in RAP proteins. The product of this gene counteracts the mitogenic function of RAS because it can interact with RAS GAPs and RAF in a competitive manner. Two transcript variants encoding the same protein have been identified for this gene.
Gene ID
5906
Gene Name (Vector)
RAP1A, member of RAS oncogene family
Gene Symbol
RAP1A
HGNC ID
HGNC:9855
ORF Size (aa)
555
RefSeq ID
NM_002884
RefSeq Synonyms
NM_002884, NM_001291896, NM_001010935, BC014086,
Species
human
UniGene ID
Hs.190334
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.