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human RAB21 shRNA silencing Adenovirus

Name 
Ad-h-RAB21-shRNA
Cat No 
shADV-220510
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human RAB21.

shADV-220510
Ad-h-RAB21-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human RAB21 (RAB21, member RAS oncogene family). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
GTP-binding protein RAB21; ras-related protein Rab-21
Description (eCommerce)
RAB21 belongs to the Rab family of monomeric GTPases, which are involved in the control of cellular membrane traffic. RAB21 plays a role in the targeted trafficking of integrins via its association with integrin alpha tails. As a consequence, RAB21 is involved in the regulation of cell adhesion and migration [taken from NCBI Entrez Gene (Gene ID: 23011)].
Description (Vector)
RAB21 belongs to the RAB family of small GTP-binding proteins that regulate intracellular vesicle targeting (Opdam et al., 2000 (PubMed 10887961)).(supplied by OMIM, Nov 2008)
Gene ID
23011
Gene Name (eCommerce)
RAB21, member RAS oncogene family
Gene Name (Vector)
RAB21, member RAS oncogene family
Gene Symbol
RAB21
HGNC ID
HGNC:18263
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
678
Protein Name (eCommerce)
Ras-related protein Rab-21
RefSeq ID
NM_014999
RefSeq Synonyms
NM_014999, BC092475, BC021901,
Research Areas
Golgi Apparatus
Research Areas (Faceted)
cell_biology
Species
human
Target Sentence
RAB21 belongs to the Rab family of monomeric GTPases, which are involved in the control of cellular membrane traffic. RAB21 plays a role in the targeted trafficking of integrins via its association with integrin alpha tails. As a consequence, RAB21 is involved in the regulation of cell adhesion and migration [taken from NCBI Entrez Gene (Gene ID: 23011)].
UniGene ID
Hs.524590
UniProt ID (eCommerce)
Q9UL25

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.