human RAB11FIP1 shRNA silencing Adenovirus

Name 
Ad-h-RAB11FIP1-shRNA
Cat No 
shADV-220492
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human RAB11FIP1.

shADV-220492
Ad-h-RAB11FIP1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human RAB11FIP1 (RAB11 family interacting protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
NOEL1A; Rab effector protein; RAB11 coupling protein; RAB11 family interacting protein 1 (class I); rab11 family-interacting protein 1; rab11-FIP1; Rab-coupling protein; Rab-interacting recycling protein; RCP
Description (eCommerce)
RAB11 coupling protein (RCP) is a Rab11 effector protein involved in the endosomal recycling process. RCP is also involved in controlling membrane trafficking along the phagocytic pathway and in phagocytosis [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q6WKZ4].
Description (Vector)
Proteins of the large Rab GTPase family (see RAB1A; MIM 179508) have regulatory roles in the formation, targeting, and fusion of intracellular transport vesicles. RAB11FIP1 is one of many proteins that interact with and regulate Rab GTPases (Hales et al., 2001 (PubMed 11495908)).(supplied by OMIM, Mar 2008)
Gene ID
80223
Gene Name (eCommerce)
RAB11 family interacting protein 1
Gene Name (Vector)
RAB11 family interacting protein 1
Gene Symbol
RAB11FIP1
HGNC ID
HGNC:30265
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1950
ORF Size (bp)
1950 bp
Protein Name (eCommerce)
Rab11 family-interacting protein 1
RefSeq ID
NM_025151
RefSeq Synonyms
NM_025151, NM_001002814, BC077720,
Research Areas
Transport
Research Areas (Faceted)
cell_biology
Species
human
Target Sentence
RAB11 coupling protein (RCP) is a Rab11 effector protein involved in the endosomal recycling process. RCP is also involved in controlling membrane trafficking along the phagocytic pathway and in phagocytosis [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q6WKZ4].
UniGene ID
Hs.696035
UniProt ID (eCommerce)
Q6WKZ4

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.