human RAB10 shRNA silencing Adenovirus

Name
Ad-h-RAB10-shRNA

Cat No
shADV-220489

Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human RAB10.

shADV-220489

Ad-h-RAB10-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human RAB10 (RAB10, member RAS oncogene family). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

55

shRNA Validated

Yes

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

GTP-binding protein RAB10; ras-related GTP-binding protein; ras-related protein Rab-10

Description (eCommerce)

GTP-binding protein RAB10 belongs to the RAS (see HRAS; MIM 190020) superfamily of small GTPases. RAB proteins localize to exocytic and endocytic compartments and regulate intracellular vesicle trafficking (Bao et al., 1998 [PubMed 9918381]) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P61026].

Description (Vector)

RAB10 belongs to the RAS (see HRAS; MIM 190020) superfamily of small GTPases. RAB proteins localize to exocytic and endocytic compartments and regulate intracellular vesicle trafficking (Bao et al., 1998 (PubMed 9918381)).(supplied by OMIM, Mar 2009)

Gene ID

10890

Gene Name (eCommerce)

RAB10, member RAS oncogene family

Gene Name (Vector)

RAB10, member RAS oncogene family

Gene Symbol

RAB10

HGNC ID

HGNC:9759

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

603

Protein Name (eCommerce)

Ras-related protein Rab-10

RefSeq ID

NM_016131

RefSeq Synonyms

NM_016131, BC000896,

Research Areas

Axonogenesis,Golgi Apparatus,Neurobiology,Neurodevelopment

Research Areas (Faceted)

cell_biology,developmental_biology,neurobiology

Species

human

Target Sentence

GTP-binding protein RAB10 belongs to the RAS (see HRAS; MIM 190020) superfamily of small GTPases. RAB proteins localize to exocytic and endocytic compartments and regulate intracellular vesicle trafficking (Bao et al., 1998 [PubMed 9918381]) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P61026].

UniGene ID

Hs.643072

UniProt ID (eCommerce)

P61026

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.