human PTPRT shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human PTPRT.
shADV-220363
Ad-h-PTPRT-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human PTPRT (protein tyrosine phosphatase, receptor type T). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
RPTPrho
Description (Vector)
PTPRT is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracellular catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP (MAM) domain, Ig-like and fibronectin type III-like repeats. The protein domain structure and the expression pattern of the mouse counterpart of this PTP suggest its roles in both signal transduction and cellular adhesion in the central nervous system. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported.
Gene ID
11122
Gene Name (Vector)
protein tyrosine phosphatase, receptor type T
Gene Symbol
PTPRT
HGNC ID
HGNC:9682
ORF Size (aa)
4383
ORF Size (bp)
4383 bp
RefSeq ID
NM_007050
RefSeq Synonyms
NM_133170, NM_007050, BC166683, BC153300,
Species
human
UniGene ID
Hs.526879
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.