human PTPRG shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human PTPRG.
shADV-220344
Ad-h-PTPRG-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human PTPRG (protein tyrosine phosphatase, receptor type G). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
HPTPG; PTPG; R-PTP-GAMMA; RPTPG
Description (Vector)
PTPRG is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this PTP contains a carbonic anhydrase-like (CAH) domain, which is also found in the extracellular region of PTPRBETA/ZETA. This gene is located in a chromosomal region that is frequently deleted in renal cell carcinoma and lung carcinoma, thus is thought to be a candidate tumor suppressor gene.
Gene ID
5793
Gene Name (Vector)
protein tyrosine phosphatase, receptor type G
Gene Symbol
PTPRG
HGNC ID
HGNC:9671
ORF Size (aa)
4251
ORF Size (bp)
4251 bp
RefSeq ID
NM_002841
RefSeq Synonyms
NM_002841, BC144110, BC140904,
Species
human
UniGene ID
Hs.654488
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.