human PTCH2 shRNA silencing Adenovirus

Name 
Ad-h-PTCH2-shRNA
Cat No 
shADV-220215
Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human PTCH2.

shADV-220215
Ad-h-PTCH2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human PTCH2 (patched 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
PTC2
Description (Vector)
PTCH2 encodes a transmembrane receptor of the patched gene family. The encoded protein may function as a tumor suppressor in the hedgehog signaling pathway. Alterations in this gene have been associated with nevoid basal cell carcinoma syndrome, basal cell carcinoma, medulloblastoma, and susceptibility to congenital macrostomia. Alternatively spliced transcript variants have been described.
Gene ID
8643
Gene Name (Vector)
patched 2
Gene Symbol
PTCH2
HGNC ID
HGNC:9586
ORF Size (aa)
3609
ORF Size (bp)
3609 bp
RefSeq ID
NM_003738
RefSeq Synonyms
NM_003738, NM_001166292, BC152911,
Species
human
UniGene ID
Hs.591497

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.