human PSME4 shRNA silencing Adenovirus

Name 
Ad-h-PSME4-shRNA
Cat No 
shADV-220183
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human PSME4.

shADV-220183
Ad-h-PSME4-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human PSME4 (proteasome activator subunit 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
PA200; proteasome (prosome, macropain) activator subunit 4; proteasome activator 200 kDa; proteasome activator complex subunit 4; proteasome activator PA200
Description (eCommerce)
proteasome (prosome, macropain) activator subunit 4 (PSME4) is subunit of the proteasome. PSME4 has been found to activate proteasomal cleavage of peptides in an energy-independent manner and may be involved in spermatogenesis. PSME4 may also be involved in DNA repair [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q14997].
Gene ID
23198
Gene Name (eCommerce)
proteasome activator subunit 4
Gene Name (Vector)
proteasome activator subunit 4
Gene Symbol
PSME4
HGNC ID
HGNC:20635
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
5190
ORF Size (bp)
5190 bp
Protein Name (eCommerce)
Proteasome activator complex subunit 4
RefSeq ID
NM_014614
RefSeq Synonyms
NM_014614, BC113668, BC112169,
Research Areas
Antigen Processing and Presentation,Apoptosis,Cell Cycle,Cell Division,Complexome,DNA Damage/Repair,Gene Expression,Host-Virus Interactions,Immunology,Metabolism/Metabolic Process,Proteasome,RNA Processing,Spermatogenesis,Ubiquitination
Research Areas (Faceted)
cell_biology,cell_cycle,developmental_biology,genetics,immunology,infectious_disease,metabolism,transcription_translation
Species
human
Target Sentence
proteasome (prosome, macropain) activator subunit 4 (PSME4) is subunit of the proteasome. PSME4 has been found to activate proteasomal cleavage of peptides in an energy-independent manner and may be involved in spermatogenesis. PSME4 may also be involved in DNA repair [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q14997].
UniGene ID
Hs.413801
UniProt ID (eCommerce)
Q14997

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.