human PPY shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human PPY.
shADV-219698
Ad-h-PPY-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human PPY (pancreatic polypeptide). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
PNP; PP
Description (Vector)
PPY belongs to the NPY family and it encodes a protein that is synthesized as a 95 aa polypeptide precursor in the pancreatic islets of Langerhans. It is cleaved into two peptide products; the active hormone of 36 aa and an icosapeptide of unknown function. The hormone acts as a regulator of pancreatic and gastrointestinal functions and may be important in the regulation of food intake. Plasma level of this hormone has been shown to be reduced in conditions associated with increased food intake and elevated in anorexia nervosa. In addition, infusion of this hormone in obese rodents has shown to decrease weight gain.
Gene ID
5539
Gene Name (Vector)
pancreatic polypeptide
Gene Symbol
PPY
HGNC ID
HGNC:9327
ORF Size (aa)
288
RefSeq ID
NM_002722
RefSeq Synonyms
NM_002722, NM_001319209, BC040033, BC032225,
Species
human
UniGene ID
Hs.558368
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.