human PPP2R3A shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human PPP2R3A.
shADV-219656
Ad-h-PPP2R3A-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human PPP2R3A (protein phosphatase 2 regulatory subunit B”alpha). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
PPP2R3; PR130; PR72
Description (Vector)
PPP2R3A encodes one of the regulatory subunits of the protein phosphatase 2. Protein phosphatase 2 (formerly named type 2A) is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2 holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B'' family. The B'' family has been further divided into subfamilies. The product of this gene belongs to the alpha subfamily of regulatory subunit B''. Alternative splicing results in multiple transcript variants encoding different isoforms.
Gene ID
5523
Gene Name (Vector)
protein phosphatase 2 regulatory subunit B''alpha
Gene Symbol
PPP2R3A
HGNC ID
HGNC:9307
ORF Size (aa)
3453
ORF Size (bp)
3453 bp
RefSeq ID
NM_002718
RefSeq Synonyms
NM_181897, NM_002718, NM_001190447, BC065531,
Species
human
UniGene ID
Hs.518155
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.