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human PPP1R8 shRNA silencing Adenovirus

Name 
Ad-h-PPP1R8-shRNA
Cat No 
shADV-219644
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human PPP1R8.

shADV-219644
Ad-h-PPP1R8-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human PPP1R8 (protein phosphatase 1 regulatory subunit 8). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
ARD-1; ARD1; NIPP-1; NIPP1; PRO2047
Description (Vector)
This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA.
Gene ID
5511
Gene Name (Vector)
protein phosphatase 1 regulatory subunit 8
Gene Symbol
PPP1R8
HGNC ID
HGNC:9296
ORF Size (aa)
630
RefSeq ID
NM_002713
RefSeq Synonyms
NM_138558, NM_014110, NM_002713, BC093017, BC013360,
Species
human
UniGene ID
Hs.533474

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.