human PPAP2B shRNA silencing Adenovirus

Name 
Ad-h-PPAP2B-shRNA
Cat No 
shADV-219500
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human PLPP3.

shADV-219500
Ad-h-PPAP2B-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human PLPP3 (phospholipid phosphatase 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
Dri42; LPP3; PAP2B; PPAP2B; VCIP
Description (Vector)
PPAP2B is a member of the phosphatidic acid phosphatase (PAP) family. PAPs convert phosphatidic acid to diacylglycerol, and function in de novo synthesis of glycerolipids as well as in receptor-activated signal transduction mediated by phospholipase D. This protein is a membrane glycoprotein localized at the cell plasma membrane. It has been shown to actively hydrolyze extracellular lysophosphatidic acid and short-chain phosphatidic acid. The expression of this gene is found to be enhanced by epidermal growth factor in Hela cells.
Gene ID
8613
Gene Name (Vector)
phospholipid phosphatase 3
Gene Symbol
PLPP3
HGNC ID
HGNC:9229
ORF Size (aa)
936
RefSeq ID
NM_003713
RefSeq Synonyms
NM_003713, BC009196,
Species
human
UniGene ID
Hs.715848

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.