human POMP shRNA silencing Adenovirus

Name 
Ad-h-POMP-shRNA
Cat No 
shADV-219435
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human POMP.

shADV-219435
Ad-h-POMP-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human POMP (proteasome maturation protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
C13orf12; HSPC014; PNAS-110; UMP1
Description (Vector)
POMP is a molecular chaperone that binds 20S preproteasome components and is essential for 20S proteasome formation. The 20S proteasome is the proteolytically active component of the 26S proteasome complex. The encoded protein is degraded before the maturation of the 20S proteasome is complete. A variant in the 5' UTR of this gene has been associated with KLICK syndrome, a rare skin disorder.
Gene ID
51371
Gene Name (Vector)
proteasome maturation protein
Gene Symbol
POMP
HGNC ID
HGNC:20330
ORF Size (aa)
426
RefSeq ID
NM_015932
RefSeq Synonyms
NM_015932, BC014334, BC003390,
Species
human
UniGene ID
Hs.268742

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.