human POLD1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human POLD1.
shADV-219347
Ad-h-POLD1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human POLD1 (DNA polymerase delta 1, catalytic subunit). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CDC2; CDC2 homolog; CRCS10; DNA polymerase delta catalytic subunit; DNA polymerase subunit delta p125; MDPL; POLD; polymerase (DNA directed), delta 1, catalytic subunit 125kDa; polymerase (DNA) delta 1, catalytic subunit
Description (eCommerce)
DNA polymerase delta catalytic subunit (PolD1) is the 125-kDa catalytic subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair [taken from NCBI Entrez Gene (Gene ID: 5424)].
Description (Vector)
POLD1 encodes the 125-kDa catalytic subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 6.
Gene ID
5424
Gene Name (eCommerce)
DNA polymerase delta 1, catalytic subunit
Gene Name (Vector)
DNA polymerase delta 1, catalytic subunit
Gene Symbol
POLD1
HGNC ID
HGNC:9175
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3324
ORF Size (bp)
3324 bp
Protein Name (eCommerce)
DNA polymerase delta catalytic subunit
RefSeq ID
NM_002691
RefSeq Synonyms
NM_002691, NM_001308632, NM_001256849, BC008800,
Research Areas
Cell Cycle,DNA Damage/Repair,DNA Replication,Homologous Recombination,Host-Virus Interactions,Replication,Telomeric Maintenance,Zinc-finger
Research Areas (Faceted)
cell_biology,cell_cycle,genetics,transcription_translation,infectious_disease
Species
human
Target Sentence
DNA polymerase delta catalytic subunit (PolD1) is the 125-kDa catalytic subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair [taken from NCBI Entrez Gene (Gene ID: 5424)].
UniGene ID
Hs.279413
UniProt ID (eCommerce)
P28340
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.