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human PLA2G12A shRNA silencing Adenovirus

Name 
Ad-h-PLA2G12A-shRNA
Cat No 
shADV-219056
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human PLA2G12A.

shADV-219056
Ad-h-PLA2G12A-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human PLA2G12A (phospholipase A2 group XIIA). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
GXII; PLA2G12; ROSSY
Description (Vector)
Secreted phospholipase A2 (sPLA2) enzymes liberate arachidonic acid from phospholipids for production of eicosanoids and exert a variety of physiologic and pathologic effects. Group XII sPLA2s, such as PLA2G12A, have relatively low specific activity and are structurally and functionally distinct from other sPLA2s (Gelb et al., 2000 (PubMed 11031251)).(supplied by OMIM, Mar 2008)
Gene ID
81579
Gene Name (Vector)
phospholipase A2 group XIIA
Gene Symbol
PLA2G12A
HGNC ID
HGNC:18554
ORF Size (aa)
570
RefSeq ID
NM_030821
RefSeq Synonyms
NM_030821, BC017218,
Species
human
UniGene ID
Hs.389452

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.