human PIK3R5 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human PIK3R5.
shADV-218963
Ad-h-PIK3R5-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human PIK3R5 (phosphoinositide-3-kinase regulatory subunit 5). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
F730038I15Rik; FOAP-2; p101; P101-PI3K
Description (Vector)
Phosphatidylinositol 3-kinases (PI3Ks) phosphorylate the inositol ring of phosphatidylinositol at the 3-prime position, and play important roles in cell growth, proliferation, differentiation, motility, survival and intracellular trafficking. The PI3Ks are divided into three classes: I, II and III, and only the class I PI3Ks are involved in oncogenesis. This gene encodes the 101 kD regulatory subunit of the class I PI3K gamma complex, which is a dimeric enzyme, consisting of a 110 kD catalytic subunit gamma and a regulatory subunit of either 55, 87 or 101 kD. This protein recruits the catalytic subunit from the cytosol to the plasma membrane through high-affinity interaction with G-beta-gamma proteins. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been found.
Gene ID
23533
Gene Name (Vector)
phosphoinositide-3-kinase regulatory subunit 5
Gene Symbol
PIK3R5
HGNC ID
HGNC:30035
ORF Size (aa)
1485
ORF Size (bp)
1485 bp
RefSeq ID
NM_014308
RefSeq Synonyms
NM_014308, NM_001251855, NM_001251853, NM_001251852, NM_001251851, NM_001142633, BC028212,
Species
human
UniGene ID
Hs.278901
Recently Viewed Products
Ad-CMV-Luc
Cat No: 1000
Ad-CMV-Akt1 (Myr)
Cat No: 1020
Ad-CMV-Akt1 (dn)
Cat No: 1021
Ad-CMV-Akt1 (wt)
Cat No: 1022
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.