human PHF12 shRNA silencing Adenovirus

Name 
Ad-h-PHF12-shRNA
Cat No 
shADV-218800
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human PHF12.

shADV-218800
Ad-h-PHF12-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human PHF12 (PHD finger protein 12). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
PF1; PHD factor 1; PHD finger protein 12; PHD zinc finger transcription factor
Description (eCommerce)
PHD factor 1 (PF1) was identified as a protein that interacts with mSin3A-histone deacetylase corepressor, a multiprotein complex that mediates transcriptional repression. PF1 is a plant homeodomain zinc finger protein that also bears a forkhead-associated (FHA) domain. PF1 appears to facilitate the recruitment of the mSin3A complex to DNA for transcriptional repression. It has also been shown to interact with the histone deacetylase containing corepressor transducin-like enhancer of split (TLE) and may play a role in bridging the mSin3A and TLE transcriptional networks.
Gene ID
57649
Gene Name (eCommerce)
PHD finger protein 12
Gene Name (Vector)
PHD finger protein 12
Gene Symbol
PHF12
HGNC ID
HGNC:20816
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2550
ORF Size (bp)
2550 bp
Protein Name (eCommerce)
PHD finger protein 12
RefSeq ID
NM_020889
RefSeq Synonyms
NM_020889, NM_001290131, NM_001033561, BC121044, BC121043, BC110882,
Research Areas
Transcription Factor/Regulator,Zinc-finger
Research Areas (Faceted)
cell_biology,transcription_translation
Species
human
Target Sentence
PHD factor 1 (PF1) was identified as a protein that interacts with mSin3A-histone deacetylase corepressor, a multiprotein complex that mediates transcriptional repression. PF1 is a plant homeodomain zinc finger protein that also bears a forkhead-associated (FHA) domain. PF1 appears to facilitate the recruitment of the mSin3A complex to DNA for transcriptional repression. It has also been shown to interact with the histone deacetylase containing corepressor transducin-like enhancer of split (TLE) and may play a role in bridging the mSin3A and TLE transcriptional networks.
UniGene ID
Hs.714975
UniProt ID (eCommerce)
Q96QT6

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.