human PHC1 shRNA silencing Adenovirus

Name
Ad-h-PHC1-shRNA

Cat No
shADV-218789

Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human PHC1.

shADV-218789

Ad-h-PHC1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human PHC1 (polyhomeotic homolog 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

shRNA Validated

Yes

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

EDR1; HPH1; MCPH11; RAE28

Description (Vector)

PHC1 is a homolog of the Drosophila polyhomeotic gene, which is a member of the Polycomb group of genes. The gene product is a component of a multimeric protein complex that contains EDR2 and the vertebrate Polycomb protein BMH1. The gene product, the EDR2 protein, and the Drosophila polyhomeotic protein share 2 highly conserved domains, named homology domains I and II. These domains are involved in protein-protein interactions and may mediate heterodimerization of the protein encoded by this gene and the EDR2 protein.

Gene ID

1911

Gene Name (Vector)

polyhomeotic homolog 1

Gene Symbol

PHC1

HGNC ID

HGNC:3182

ORF Size (aa)

2874

ORF Size (bp)

2874 bp

RefSeq ID

NM_004426

RefSeq Synonyms

NM_004426, BC157850, BC073964, BC017748,

Species

human

UniGene ID

Hs.305985

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.