human PDZK1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human PDZK1.
shADV-218579
Ad-h-PDZK1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human PDZK1 (PDZ domain containing 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CAP70; CLAMP; NHERF-3; NHERF3; PDZD1
Description (Vector)
PDZK1 encodes a PDZ domain-containing scaffolding protein. PDZ domain-containing molecules bind to and mediate the subcellular localization of target proteins. The encoded protein mediates the localization of cell surface proteins and plays a critical role in cholesterol metabolism by regulating the HDL receptor, scavenger receptor class B type 1. Single nucleotide polymorphisms in this gene may be associated with metabolic syndrome, and overexpression of this gene may play a role in drug resistance of multiple myeloma. Pseudogenes of this gene are located on the long arm of chromosome 1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Gene ID
5174
Gene Name (Vector)
PDZ domain containing 1
Gene Symbol
PDZK1
HGNC ID
HGNC:8821
ORF Size (aa)
1560
ORF Size (bp)
1560 bp
RefSeq ID
NM_002614
RefSeq Synonyms
NM_002614, NM_001201326, NM_001201325, BC006518, BC006496,
Species
human
UniGene ID
Hs.444751
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.