human PDXP shRNA silencing Adenovirus

Name 
Ad-h-PDXP-shRNA
Cat No 
shADV-218568
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human PDXP.

shADV-218568
Ad-h-PDXP-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human PDXP (pyridoxal phosphatase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CIN; dJ37E16.5; PLP
Description (Vector)
Pyridoxal 5-prime-phosphate (PLP) is the active form of vitamin B6 that acts as a coenzyme in maintaining biochemical homeostasis. The preferred degradation route from PLP to 4-pyridoxic acid involves the dephosphorylation of PLP by PDXP (Jang et al., 2003 (PubMed 14522954)).(supplied by OMIM, Mar 2008)
Gene ID
57026
Gene Name (Vector)
pyridoxal phosphatase
Gene Symbol
PDXP
HGNC ID
HGNC:30259
ORF Size (aa)
891
RefSeq ID
NM_020315
RefSeq Synonyms
NM_020315, BC064922, BC000320,
Species
human
UniGene ID
Hs.632762

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.