human PDGFA shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human PDGFA.
shADV-218503
Ad-h-PDGFA-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human PDGFA (platelet derived growth factor subunit A). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
PDGF-A; PDGF1
Description (Vector)
PDGFA is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer or as a heterodimer with the platelet-derived growth factor beta polypeptide, where the dimers are connected by disulfide bonds. Studies using knockout mice have shown cellular defects in oligodendrocytes, alveolar smooth muscle cells, and Leydig cells in the testis; knockout mice die either as embryos or shortly after birth. Two splice variants have been identified for this gene.
Gene ID
5154
Gene Name (Vector)
platelet derived growth factor subunit A
Gene Symbol
PDGFA
HGNC ID
HGNC:8799
ORF Size (aa)
588
RefSeq ID
NM_033023
RefSeq Synonyms
NM_033023, NM_002607, BC146594, BC141593,
Species
human
UniGene ID
Hs.535898
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.