human PDCD2 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human PDCD2.
shADV-218439
Ad-h-PDCD2-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human PDCD2 (programmed cell death 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
programmed cell death protein 2; RP8; zinc finger MYND domain-containing protein 7; zinc finger protein Rp-8; ZMYND7
Description (eCommerce)
Programmed cell death 2 (PDCD2) is a nuclear protein expressed in a variety of tissues. Expression of PDCD2 has been shown to be repressed by B-cell CLL/lymphoma 6 (BCL6), a transcriptional repressor required for lymph node germinal center development, suggesting that BCL6 regulates apoptosis by its effects on this protein [taken from NCBI Entrez Gene (Gene ID: 5134)].
Description (Vector)
PDCD2 encodes a nuclear protein expressed in a variety of tissues. Expression of this gene has been shown to be repressed by B-cell CLL/lymphoma 6 (BCL6), a transcriptional repressor required for lymph node germinal center development, suggesting that BCL6 regulates apoptosis by its effects on this protein. Alternative splicing results in multiple transcript variants and pseudogenes have been identified on chromosomes 9 and 12.
Gene ID
5134
Gene Name (eCommerce)
programmed cell death 2
Gene Name (Vector)
programmed cell death 2
Gene Symbol
PDCD2
HGNC ID
HGNC:8762
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1035
ORF Size (bp)
1035 bp
Protein Name (eCommerce)
Programmed cell death protein 2
RefSeq ID
NM_002598
RefSeq Synonyms
NM_144781, NM_002598, NM_001199464, NM_001199463, NM_001199462, NM_001199461, BC008378,
Research Areas
Apoptosis,Signal Transduction,TNF Signaling,Zinc-finger
Research Areas (Faceted)
signal_transduction,cell_biology
Species
human
Target Sentence
Programmed cell death 2 (PDCD2) is a nuclear protein expressed in a variety of tissues. Expression of PDCD2 has been shown to be repressed by B-cell CLL/lymphoma 6 (BCL6), a transcriptional repressor required for lymph node germinal center development, suggesting that BCL6 regulates apoptosis by its effects on this protein [taken from NCBI Entrez Gene (Gene ID: 5134)].
UniGene ID
Hs.367900
UniProt ID (eCommerce)
Q16342
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.