human PCMT1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human PCMT1.
shADV-218387
Ad-h-PCMT1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human PCMT1 (protein-L-isoaspartate (D-aspartate) O-methyltransferase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
PIMT
Description (Vector)
PCMT1 encodes a member of the type II class of protein carboxyl methyltransferase enzymes. The encoded enzyme plays a role in protein repair by recognizing and converting D-aspartyl and L-isoaspartyl residues resulting from spontaneous deamidation back to the normal L-aspartyl form. The encoded protein may play a protective role in the pathogenesis of Alzheimer's disease, and single nucleotide polymorphisms in this gene have been associated with spina bifida and premature ovarian failure. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Gene ID
5110
Gene Name (Vector)
protein-L-isoaspartate (D-aspartate) O-methyltransferase
Gene Symbol
PCMT1
HGNC ID
HGNC:8728
ORF Size (aa)
684
RefSeq ID
NM_005389
RefSeq Synonyms
NM_005389, NM_001252053, NM_001252052, NM_001252051, NM_001252050, NM_001252049, BC008748, BC007501,
Species
human
UniGene ID
Hs.279257
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.