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human PANK4 shRNA silencing Adenovirus

Name 
Ad-h-PANK4-shRNA
Cat No 
shADV-218177
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human PANK4.

shADV-218177
Ad-h-PANK4-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human PANK4 (pantothenate kinase 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
60
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
hPanK4; pantothenate kinase 4; pantothenic acid kinase 4
Description (eCommerce)
Pantothenate kinase 4 (PanK4) belongs to the pantothenate kinase family. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. PanK4 catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by CoA. This family member is most abundant in muscle but is expressed in all tissues [taken from NCBI Entrez Gene (Gene ID: 55229)].
Description (Vector)
PANK4 encodes a protein belonging to the pantothenate kinase family. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by CoA. This family member is most abundant in muscle but is expressed in all tissues.
Gene ID
55229
Gene Name (eCommerce)
pantothenate kinase 4
Gene Name (Vector)
pantothenate kinase 4
Gene Symbol
PANK4
HGNC ID
HGNC:19366
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2322
ORF Size (bp)
2322 bp
Protein Name (eCommerce)
Pantothenate kinase 4
RefSeq ID
NM_018216
RefSeq Synonyms
NM_018216, BC043496,
Research Areas
Metabolism/Metabolic Process
Research Areas (Faceted)
cell_biology,metabolism
Species
human
Target Sentence
Pantothenate kinase 4 (PanK4) belongs to the pantothenate kinase family. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. PanK4 catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by CoA. This family member is most abundant in muscle but is expressed in all tissues [taken from NCBI Entrez Gene (Gene ID: 55229)].
UniGene ID
Hs.26156
UniProt ID (eCommerce)
Q9NVE7

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.