human AKAP2 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human AKAP2.
shADV-218165
Ad-h-AKAP2-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human AKAP2 (A-kinase anchoring protein 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
A kinase (PRKA) anchor protein 2; AKAP-2; AKAPKL; AKAP-KL; A-kinase anchor protein 2; MISP2; PRKA2; protein kinase A anchoring protein 2; protein kinase A2; Protein kinase A-anchoring protein 2
Description (eCommerce)
AKAP2 (A-kinase anchoring protein 2) was identified in a yeast two-hybrid screen as a protein that interacts with protein kinase A (PKA). AKAP2 functions to direct the subcellular localization of PKA and may also function as a link for cytoskeletal signaling complexes. Structurally, AKAP2 contains two tandem RGS domains, a PKA-binding motif, and a PDZ (PSD95/Dlg/ZO1)-binding motif.
Description (Vector)
AKAP2 binds to the regulatory subunit of protein kinase A and is found associated with the actin cytoskeleton. The encoded protein mediates signals carried by cAMP and may be involved in creating polarity in certain signaling processes. Three transcript variants encoding different isoforms have been found for this gene.
Gene ID
11217
Gene Name (eCommerce)
A-kinase anchoring protein 2
Gene Name (Vector)
A-kinase anchoring protein 2
Gene Symbol
AKAP2
HGNC ID
HGNC:372
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2847
ORF Size (bp)
2847 bp
Protein Name (eCommerce)
A-kinase anchor protein 2
RefSeq ID
NM_001004065
RefSeq Synonyms
NM_001198656, NM_001136562, NM_001004065, BC171800, BC146863,
Research Areas
Signal Transduction
Research Areas (Faceted)
signal_transduction
Species
human
Target Sentence
AKAP2 (A-kinase anchoring protein 2) was identified in a yeast two-hybrid screen as a protein that interacts with protein kinase A (PKA). AKAP2 functions to direct the subcellular localization of PKA and may also function as a link for cytoskeletal signaling complexes. Structurally, AKAP2 contains two tandem RGS domains, a PKA-binding motif, and a PDZ (PSD95/Dlg/ZO1)-binding motif.
UniGene ID
Hs.591908
UniProt ID (eCommerce)
Q9Y2D5
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.